Welcome to Applied Clinical Omics technologies for Personalized medicine




Description:

Omics technologies including genomics, transcriptomics, proteomics and metabolomics are now key technologies in multiple fields of research and a highly active domain in health and medical investigation. Omics is an interdisciplinary research field that coalesces researchers from many different areas of biomedical research into one of the most likely disciplines to successfully foster the translation of basic scientific knowledge into clinical applications for the benefit of patients. For instance, proteomics and applied mass spectrometry are vital tools to investigate the human proteome in a clinical perspective (www.hupo.org).

 

This PhD course will focus on advanced theoretical and practical aspects of Omics strategies in life sciences as well as medical research. Our focus will address the application of omics strategies to address a diverse range of medical pathologies, including but not limited to autoimmune disorders, diseases associated to neuro-inflammation and neurodegeneration as well as chronic pain conditions. Omics are currently utilized extensively to identify biomarker patterns for detection of disease risk, patient’s stratification, identification of responders to a particular treatment, or elucidation of mechanism of disease or drug action with the ultimate goal of patient safety and better health outcome.

The course will be a combination of lectures and laboratory demonstrations with a hands-on experimental part. Considering the value and importance of omics, and a rapidly growing trend, this course aims at providing front edge information about current advanced methodologies applied in medical omics through real-life examples. Hence, participants will be able to translate the presented strategies and methods into their own health and medical related research.

 

Lectures:

  • Theoretical and strategic introduction to omics technologies in the scope of clinical research.
  • Strategies for clinical proteomics, genomics and metabolomics for personalized medicine in several fields including autoimmune disorders, neurodegenerative diseases and chronic pain.
  • Project design for omics type projects
  • Sample handling from patients (biobank), animal models, or in-vitro systems to the mass spectrometer and beyond
  • Principles of mass spectrometry and sample preparation for MS
  • Applications for quantitative proteomics and metabolomics in health and medical science.

 

Literature
Notes, literature and exercise instruction will be distributed at the course

 

Prerequisites
None

 

Evaluation

Active participation in the theoretical and experimental course

Organizer: Associate professor Allan Stensballe, email: as@hst.aau.dk

Lecturers: Associate Professor Allan Stensballe, Assistant Professor Parisa Gazerani, Assistant Professor Tue Bjerg Bennike, Aalborg University,Staff Scientist Michael Kruse Meyer and invited lectures

ECTS: 2.5

Time: 19, 20 and 21 June 2019 (19.6 and 20.6: 8.15 - 16.15; 21.6: 8.15 - 12.00)



Place: Aalborg University, Fredrik Bajers Vej 7E, room E3-209  

Zip code: 
Aalborg Øst

City: 
9220

Number of seats:

Deadline: 29 May 2019 

Important information concerning PhD courses: We have over some time experienced problems with no-show for both project and general courses. It has now reached a point where we are forced to take action. Therefore, the Doctoral School has decided to introduce a no-show fee of DKK 5,000 for each course where the student does not show up. Cancellations are accepted no later than 2 weeks before start of the course. Registered illness is of course an acceptable reason for not showing up on those days. Furthermore, all courses open for registration approximately three months before start. This can hopefully also provide new students a chance to register for courses during the year. We look forward to your registrations.