Description The course will focus on the importance of method comparison studies when evaluating new clinical and experimental methods. The course will describe how method comparison studies are designed and how obtained results are analysed and described. Application of analytical measures such as Coefficient of Variance, Intra-Class Correlation, differences in means, and Bland-Altman’s limits of agreement, inter-rater reliability, test accuracy and sample size estimation will be discussed. The aim of the course is to provide the participants with a toolbox that enables them to perform and analyse method comparison studies. This advanced course in biostatistics assumes knowledge of basic methods in biostatistics, including the concepts of hypothesis testing, and basic study designs. The course is designed for researchers working in both clinical and experimental settings.

Organiser: Professor Lars J. Petersen, e-mail:

Lecturers: Assistant Professor José Alberto Biurrun Manresa, Professor Lars J. Petersen, Associate Professor Carsten Dahl Mørch, Aalborg University

ECTS: 1.5 ECTS (subject to changes)

Dates: 8.-9. December 2015

Place: Forskningens Hus, Sdr. Skovvej 15, 9000 Aalborg, lokale 106

Deadline: 17 November, 2015

Atkinson G, Nevill A. Statistical methods for assessing measurement error (reliability) in variables relevant to sports medicine. Sports Med 1998; 26: 217-238,

Weir JP. Quantifying test-retest reliability using the intraclass correlation coefficient and the SEM. Journal of Strength and Conditioning Research 2005; 19: 231–240

Bland JM, Altman DG. Measuring agreement in method comparison studies. Statistical Methods in Medical Research 1999; 8: 135 – 160

Links, data-sets and handouts distributes prior to and during the course.

Basic knowledge on statistics (e.g. Biostatistics I)

Short project/assignment