Description: This course is intended to provide an introduction to basic principles related to designing and using acute and chronic animal models in biomedical engineering research. As practically all therapeutic agents and devices and many therapeutic methods require animal testing before application to humans, the use of animal models is common in biomedical engineering research. Moreover, the use of animal models in the process of developing new therapeutic agents, devices and methods allows investigation of basic mechanisms supporting the action of those therapeutic means, which is rarely possible in human studies. Gaining such knowledge is important not only to advance the understanding in the field of research, but also to provide means for further development and optimization of the investigated therapies. In those respects, the course will address relevant issues related to theoretical and practical aspects in regard to designing and developing animal models for acute and chronic investigation of therapeutic agents, devices and methods. General principles and specific examples regarding those issues, as well as means to combine basic and application-oriented research will be discussed. Students are most welcome to address and discuss issues related to possibilities of using animal models in their own research projects.

1. Ethical aspects related to animal studies.
2. Applying for ethical approval to perform animal studies in Denmark.
3. Most common laboratory animals used in the labs affiliated to Aalborg University. Choosing a proper laboratory animal for developing an animal model.
4. Facilities and techniques related to animal studies available at Aalborg University and Aalborg University Hospital. Labs tours.
5. Principles in developing animal models. Acute and chronic animal models developed at Aalborg University.
6. Combining application-oriented research with basic research studies.
7. Fabrication and micro-fabrication of investigational tools. Designing of experimental setups for acute and chronic animals studies.

Lecture notes. Selected papers and book chapters may also be indicated shortly before the course.

Basic knowledge in animal anatomy/physiology and biomedical principles.

Written assignment.

Organizer: Associate Professor Cristian Sevcencu, e-mail:

Lecturers: Associate Professor Cristian Sevcencu, Aalborg University, and invited lecturers

ECTS: 1.5 (subject to changes)

Time: 6., 12. november og 3. december 2015 (8.15-12.00)

Place: Aalborg University, Fredrik Bajers Vej 7E, room E3-109

Zip code: 9220

City: Aalborg

Number of seats:

Deadline: 9 October, 2015