Couse name: Disease-related malnutrition
PhD Programme: Clinical Science and Laboratory and Translational Medicine
Description: This PhD course aims at providing thorough, reflective, and reflexive knowledge on the overall aspects of disease related malnutrition and is especially intended for students with clinical projects. Moreover, this course aims to meet students’ needs in addition to covering essential elements of clinical research and evidence-based practice. Additionally, the course will attend especially to the issue of translational nutrition from the more cell based experimental nutrition over clinical nutrition to applied research methods. Prerequisites:
Students enrolled in PhD program and at a point where they have finished their general courses. Students doing quantitative and mixed method research in nutrition, regardless of research setting, are encouraged to apply for this course
Learning objectives. After the course the students should be able to: Explain the scientific basis and relevance and relevance of disease related malnutrition. Decide on scientific approaches and methodologies special for clinical nutrition research.
Teaching methods: This course will be run in a combined lecture and workshop style and the students will be encouraged to active participation.
Organizer: Mette Holst, Professor, Head of Research, PhD. Centre for Nutrition and intestinal Failure, Aalborg University hospital and Department of Clinical Medicine, Aalborg University
Lecturers: Henrik Højgaard Rasmussen, Professor, Consultant, MD, PhD. Centre for Nutrition and intestinal Failure, Aalborg University hospital and Department of Clinical Medicine, Aalborg University
Randi Tobberup, Head of Dietetics, PhD. Centre for Nutrition and intestinal Failure, Aalborg University hospital
Helle Nygaard Lærke, Senior researcher, PhD. Aarhus University
Mette Holst, Professor, Head of Research, PhD. Centre for Nutrition and intestinal Failure, Aalborg University hospital and Department of Clinical Medicine, Aalborg University
ECTS: 2
Dates: 30, 31 October and 1 and 2 November
Time: 9-16
Place: Room 12.02.066 on 30 October, 1 and 2 November. Room 11.01.035 on 31 October. Address: Selma Lagerløfs Vej 249, 9260 Gistrup
Zip code: 9000
City: Aalborg
Number of seats: 20
Deadline: 9 October 2023
Important information concerning PhD courses: Criteria for assessment: Active participation in the course including brief presentation of own project and ‘methodology challenge you wish to tackle’. Presence at least three out of four days.
Online participation is not offered.
Literature/Requirements: Chapters from: Sobotka L et al. “Basics in Clinical Nutrition” Fifth. Ed. Publishing House Galèn, ISBN978-80-7492-427-9 and other literature will follow upon signing for the course.
Program:
Day 1
Welcome and introduction
Background and definitions.
Metabolism in healthy individuals, fasting and disease.
Nutritional assessment; Body composition and function (l)
Assessment of skeletal muscle mass, BIA, CT and MR
Anthropometric measures
Measures of physical function
Practical workshop
Nutritional intake in the diagnosis of malnutrition
Day 2
Nutritional Assessment (ll)
Bowel anatomy and function
Measurement of absorption and malabsorption
The role of the gut microbiota in inflammation and metabolism
Laboratory analysis and biomarkers in nutrition and inflammation
Day 3
Nutritional assessment (lll)
Nutrition Impact Symptoms (NIS) and their implications on nutrition intake
NIS assessment methods for use in clinical practice and research
Patient reported outcome measures (PROMS) for use in clinical practice and research
Nutritional treatment
Estimation and measurements of nutritional requirements in different phenotypes
Targeted nutritional therapy
1) Generalized interventions and specific therapies aimed at inflammation and body composition
2) Specific nutrients and bioactive substances targeting anabolism and inflammation
Nutrition intervention methods; Oral, enteral and parenteral
Methods for quantifying nutrition intake
Day 4
Relevant clinical outcomes in clinical nutrition
Research methods in clinical nutrition
Experimental and clinical research designs
1) Experimental: Laboratory tests, animal models, surrogate markers and power calculation
2) Clinical: Observational and intervention studies
3) Applied: Questionnaires, qualitative methods and implementation studies
Workshops will be included during the day
Important information concerning PhD courses:
We have over some time experienced problems with no-show for both project and general courses. It has now reached a point where we are forced to take action. Therefore, the Doctoral School has decided to introduce a no-show fee of DKK 3.000 for each course where the student does not show up. Cancellations are accepted no later than 2 weeks before start of the course. Registered illness is of course an acceptable reason for not showing up on those days. Furthermore, all courses open for registration approximately four months before start. This can hopefully also provide new students a chance to register for courses during the year. We look forward to your registrations.
- Teacher: Mette Holst