Description
Omics technologies including genomics, transcriptomics, epigenetics, proteomics and metabolomics are now key technologies in multiple fields of research and a highly active domain in health and medical investigation. Omics is an interdisciplinary research field that coalesces researchers from many different areas of biomedical research into one of the most likely disciplines to successfully foster the translation of basic scientific knowledge into clinical applications for the benefit of patients.
This PhD course will focus on advanced theoretical and practical aspects of Omics strategies in Life & Medical sciences. Our focus will address the clinical study design and ethical protol requirements to application of omics strategies to address a diverse range of medical pathologies, including but not limited to autoimmune disorders, diseases associated to neuro-inflammation and neurodegeneration as well as chronic pain conditions. Omics are currently utilized extensively to identify biomarker patterns for detection of disease risk, patient’s stratification, identification of responders to a particular treatment, or elucidation of mechanism of disease or drug action with ultimate goal of patient safety and better health outcome.
The course will be a combination of lectures, bioinformatics tutorials and laboratory demonstrations with hands-on experimental parts. Considering the value and importance of omics, and a rapidly growing trend, this course aims at providing front edge information about current advanced methodologies applied in medical omics through real-life examples. Hence, participants will be able to translate the presented strategies and methods into their own health, and medical related research.
Lectures & Practical
· Clinical study design and ethical aspects for Omics type projects
· Sample handling from patients (biobank), animal models, or in-vitro systems to the mass spectrometer and beyond
· Theoretical and strategic introduction to Omics technologies in scope of clinical research.
· Strategies for clinical proteomics, genomics and metabolomics for personalized medicine in several fields including autoimmune disorders, neurodegenerative diseases and chronic pain.
· Applications for quantitative proteomics and metabolomics in health and medical science.
· Statistical evaluation and presentations of Omics data in scientific publications
· Bioinformatice processing and data integration of Omics data
· Practical session – From biofluid to quantitative proteomics analysis.
Literature
Notes, literature and exercise instruction will be distributed at the course
Prerequisites
None; Background in clinical, translational or biomedical sciences is recommended.
Evaluation Active participation in the theoretical and experimental course.
Organizer: Associate professor Allan Stensballe, email: as@hst.aau.dk
Lecturers: Associate Professor Allan Stensballe; Aalborg University, Christopher Aboo; invited lectures.
ECTS: 2.5
Dates: 13 -15 December 2023
Format: Lectures (on-site); Laboratory execises (Approx 3x2hours on-site)
Place: Aalborg University
Deadline: 13-15 december 2023
Number of seats: 18
Important information concerning PhD courses:
We have over some time experienced problems with no-show for both project and general courses. It has now reached a point where we are forced to take action. Therefore, the Doctoral School has decided to introduce a no-show fee of DKK 3.000 for each course where the student does not show up. Cancellations are accepted no later than 2 weeks before start of the course. Registered illness is of course an acceptable reason for not showing up on those days. Furthermore, all courses open for registration approximately four months before start. This can hopefully also provide new students a chance to register for courses during the year. We look forward to your registrations.
- Teacher: Allan Stensballe