This course is intended to provide an introduction to basic principles related to designing and using acute and chronic animal models in the biomedical and biomedical engineering research. As practically all therapeutic agents, devices and methods require animal testing before application to humans, the use of animal models is necessary in developing such therapeutic means. Moreover, the use of animal models in the process of developing new therapeutic agents, devices and methods allows investigation of basic mechanisms supporting the action of those therapeutic means, which is rarely possible in human studies. Gaining such knowledge is important not only to advance the understanding in the field of research, but also to provide means for further development and optimization of new therapies. In those respects, the course will address relevant issues related to theoretical and practical aspects in regard to designing and developing animal models for acute and chronic investigation of therapeutic agents, devices and methods. General principles and specific examples regarding those issues, as well as methods to combine basic and application-oriented research will be discussed. Students are most welcome to address and discuss issues related to possibilities of using animal models in their own research projects.



  1. Ethical aspects related to animal studies. 
  2. Applying for ethical approval to perform animal studies in Denmark.
  3. Most common laboratory animals used in the labs affiliated to Aalborg University. Choosing a proper laboratory animal for developing an animal model.
  4. Facilities and techniques related to animal studies available at Aalborg University and Aalborg University Hospital. Labs tours.
  5. Principles in developing animal models. Acute and chronic animal models developed at Aalborg University.
  6. Combining application-oriented research with basic research studies.
  7. Fabrication and micro-fabrication of investigational tools. Designing of experimental setups for acute and chronic animals studies.



Lecture notes. Selected papers and book chapters may also be indicated shortly before the course.



Basic knowledge in animal anatomy/physiology and biomedical principles.



Written assignment.

Organizer: Associate Professor Cristian Sevcencu, email: sevcr@hst.aau.dk

Lecturers: Associate Professor Cristian Sevcencu and invited lecturers

ECTS: 1,5

Time: 22, 25 & 28 May 2018 (8.15 – 12.00)

Place: Aalborg University, Fredrik Bajers Vej 7D, room D2-106


Number of seats:

Deadline: 8 May 2018

Important information concerning PhD courses We have over some time experienced problems with no-show for both project and general courses. It has now reached a point where we are forced to take action. Therefore, the Doctoral School has decided to introduce a no-show fee of DKK 5,000 for each course where the student does not show up. Cancellations are accepted no later than 2 weeks before start of the course. Registered illness is of course an acceptable reason for not showing up on those days. Furthermore, all courses open for registration approximately three months before start. This can hopefully also provide new students a chance to register for courses during the year. We look forward to your registrations.